| Description : |
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
71 kDa |
| AA Sequence : |
MEELVVEVRGSNGAFYKAFVKDVHE DSITVAFENNWQPDRQIPFHDVRFP PPVGYNKDINESDEVEVYSRANEKE PCCWWLAKVRMIKGEFYVIEYAACD ATYNEIVTIERLRSVNPNKPATKDT FHKIKLDVPEDLRQMCAKEAAHKDF KKAVGAFSVTYDPENYQLVILSINE VTSKRAHMLIDMHFRSLRTKLSLIM RNEEASKQLESSRQLASRFHEQFIV REDLMGLAIGTHGANIQQARKVPGV TAIDLDEDTCTFHIYGEDQDAVKKA RSFLEFAEDVIQVPRNLVGKVIGKN GKLIQEIVDKSGVVRVRIEAENEKN VPQEEEIMPPNSLPSNNSRVGPNAP EEKKHLDIKENSTHFSQPNSTKVQR VLVASSVVAGESQKPELKAWQGMVP FVFVGTKDSIANATVLLDYHLNYLK EVDQLRLERLQIDEQLRQIGASSRP PPNRTDKEKSYVTDDGQGMGRGSRP YRNRGHGRRGPGYTSGTNSEASNAS ETESDHRDELSDWSLAPTEEERESF LRRGDGRRRGGGGRGQGGRGRGGGF KGNDDHSRTDNRPRNPREAKGRTTD GSLQIRVDCNNERSVHTKTLQNTSS EGSRLRTGKDRNQKKEKPDSVDGQQ PLVNGVPTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
