Recombinant Human Fms-Related Tyrosine Kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
Cat.No. : | FLT1-1221H |
Product Overview : | Recombinant humansoluble FLT1 is the naturally occurring form and was cloned from total RNA ofhuman umbilical vein endothelial cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FLT1-1221H |
Description : | The recombinant mature soluble FLT1 is aglycosylated monomeric protein consisting of the first 6 extracellulardomains (Met1-His688) containing the unique 31 amino acid residues at theC-terminus. |
Source : | Insect cells |
Species : | Human |
Form : | Lyophilizedwithout additives. |
Molecular Weight : | 96 kDa |
Purity : | > 90% asdetermined by SDS-PAGE and visualized by silver stain |
Endotoxin Level : | < 0.1 ng/µg of FLT1 |
Biological Activity : | Determined by itsability to abolish the binding of iodinated FLT1 to solid surfaces or cellsurface receptors. The ED50 for this effect is typically 10 ng/ml. The usablerange is 5-50 ng/ml. |
Reconstitution : | Centrifugevial prior to opening. Soluble in water and most aqueous buffers. Add PBS tothe vial to fully solubilize the protein to a concentration not lower than100 ng/ml. |
Storage : | Lyophilized proteinis stable for 6 months at -20°C to -80°C. Store reconstituted protein inworking aliquots at -20°C. Avoid repeated freeze-thaw cycles. |
Gene Name : | FLT1 fms-related tyrosine kinase 1(vascular endothelial growth factor/vascular permeability factor receptor) [ Homosapiens ] |
Official Symbol : | FLT1 |
Synonyms : | FLT1; fms-related tyrosinekinase 1 (vascular endothelial growth factor/vascular permeability factorreceptor); FLT; VEGFR1; FRT; vascular endothelial growth factor receptor 1;EC 2.7.10.1; VEGFR-1; Vascular permeability factor receptor; Flt-1;Tyrosine-protein kinase receptor FLT; Tyrosine-protein kinase FRT; Fms-liketyrosine kinase 1 |
Gene ID : | 2321 |
mRNA Refseq : | NM_001159920 |
Protein Refseq : | NP_001153392 |
MIM : | 165070 |
UniProt ID : | P17948 |
Chromosome Location : | 13q12 |
Pathway : | Cytokine-cytokinereceptor interaction; Endocytosis; Focal Adhesion; Glypican 1 network;HIF-2-alpha transcription factor network; Id Signaling Pathway; Neurophilininteractions with VEGF and VEGFR; Rheumatoid arthritis; S1P3 pathway; SignalTransduction; Signaling by VEGF; Signaling events mediated by VEGFR1 andVEGFR2; VEGF binds to VEGFR leading to receptor dimerization; VEGFligand-receptor interactions; VEGFR1 specific signals |
Function : | ATP binding; growth factorbinding; identical protein binding; nucleotide binding; receptor activity;transferase activity; vascular endothelial growth factor receptor activity |
Products Types
◆ Recombinant Protein | ||
Flt1-1785M | Active Recombinant Mouse Flt1 Protein, Fc-tagged | +Inquiry |
FLT1-2020R | Recombinant Rat FLT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FLT1-474H | Recombinant Human FLT1 Protein, His-tagged | +Inquiry |
FLT1-1314H | Recombinant Human FLT1 Protein (P801-L1158), His tagged | +Inquiry |
FLT1-133H | Active Recombinant Human FLT1 Protein (27-328aa), C-hIgG tagged | +Inquiry |
◆ Lysates | ||
FLT1-1207RCL | Recombinant Rat FLT1 cell lysate | +Inquiry |
FLT1-1909HCL | Recombinant Human FLT1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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