Description : |
The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
71.3 kDa |
AA Sequence : |
MSWGTELWDQFDNLEKHTQWGIDIL EKYIKFVKERTEIELSYAKQLRNLS KKYQPKKNSKEEEEYKYTSCKAFIS NLNEMNDYAGQHEVISENMASQIIV DLARYVQELKQERKSNFHDGRKAQQ HIETCWKQLESSKRRFERDCKEADR AQQYFEKMDADINVTKADVEKARQQ AQIRHQMAEDSKADYSSILQKFNHE QHEYYHTHIPNIFQKIQEMEERRIV RMGESMKTYAEVDRQVIPIIGKCLD GIVKAAESIDQKNDSQLVIEAYKSG FEPPGDIEFEDYTQPMKRTVSDNSL SNSRGEGKPDLKFGGKSKGKLWPFI KKNKLMSLLTSPHQPPPPPPASASP SAVPNGPQSPKQQKEPLSHRFNEFM TSKPKIHCFRSLKRGLSLKLGATPE DFSNLPPEQRRKKLQQKVDELNKEI QKEMDQRDAITKMKDVYLKNPQMGD PASLDHKLAEVSQNIEKLRVETQKF EAWLAEVEGRLPARSEQARRQSGLY DSQNPPTVNNCAQDRESPDGSYTEE QSQESEMKVLATDFDDEFDDEEPLP AIGTCKALYTFEGQNEGTISVVEGE TLYVIEEDKGDGWTRIRRNEDEEGY VPTSYVEVCLDKNAKDSTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |