Recombinant Human FOLH1 Protein, His-tagged, Alexa Fluor 647 conjugated

• Cat.No.: FOLH1-2416HAF647
• Product Overview: Alexa Fluor 647 conjugated recombinant human FOLH1(Lys44-Ala750), fused with His tag at N-terminal, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized
• Molecular Mass: 81.7 kDa
• Protein length: Lys44-Ala750， 725
• N-terminal Sequence Analysis: His
• Endotoxin: < 1.0 EU/ μg of the protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE
• Characteristic: Disulfide-linked homodimer
  Labeled with Alexa Fluor 647 via amines
  Excitation = 650 nm
  Emission = 668 nm
• Stability: Samples are stable for up to 12 months from date of receipt at -70 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization.

Gene Information

• Gene Name: FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 [ Homo sapiens ]
• Official Symbol: FOLH1
• Synonyms: FOLH1; folate hydrolase (prostate-specific membrane antigen) 1; FOLH; glutamate carboxypeptidase 2; GCP2; GCPII; glutamate carboxylase II; glutamate carboxypeptidase II; NAALAD1; NAALAdase; PSM; PSMA; NAALADase I; membrane glutamate carboxypeptidase; cell growth-inhibiting gene 27 protein; folylpoly-gamma-glutamate carboxypeptidase; prostate specific membrane antigen variant F; pteroylpoly-gamma-glutamate carboxypeptidase; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; FGCP; mGCP
• Gene ID: 2346
• mRNA Refseq: NM_004476
• Protein Refseq: NP_004467
• MIM: 600934
• UniProt ID: Q04609

Reviews

09/05/2019

It has been shown to play a crucial role in multiple cellular processes, making it highly valuable for investigations into cell signaling, inflammation, and immune responses.

01/28/2018

Incorporating the FOLH1 protein into your research will not only meet but exceed your expectations, enabling you to advance your scientific discoveries with confidence.

06/06/2016

Researchers can leverage the unique properties of the FOLH1 protein to gain insights into its biological functions and its impact on disease mechanisms.

Q&As

What advancements have been made in FOLH1-targeted therapies recently?

New radioligands and imaging agents with enhanced specificity and reduced off-target effects are being developed for more effective treatment.

How does targeting FOLH1 impact treatment precision?

Targeting FOLH1 helps deliver treatments directly to cancer cells, minimizing damage to healthy tissues, thus improving treatment precision.

Are there other potential applications of FOLH1 beyond prostate cancer?

Yes, research suggests potential roles in imaging and therapy for other cancers expressing FOLH1, such as renal cell carcinoma and certain types of gliomas.

Can FOLH1 be used for early cancer detection?

Yes, FOLH1-based imaging techniques show promise in detecting cancer at early stages, aiding in timely intervention and improved outcomes.

Are there ongoing clinical trials exploring FOLH1's applications?

Yes, numerous trials investigate FOLH1-targeted imaging and therapies in various cancers, aiming to expand its clinical utility.