Recombinant Human forkhead box P2 Protein, His tagged

• Cat.No.: FOXP2-093H
• Product Overview: Recombinant human FOXP2 protein (O15409) (Arg 478-Lys 596) with a His tag at the C-terminus was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 478-596aa
• Description: Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
• Tag: C-His
• Molecular Mass: 15.8 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: FOXP2 forkhead box P2 [ Homo sapiens (human) ]
• Official Symbol: FOXP2
• Synonyms: FOXP2; forkhead box P2; SPCH1, TNRC10; forkhead box protein P2; CAG repeat protein 44; CAGH44; forkhead/winged helix transcription factor; speech and language disorder 1; trinucleotide repeat containing 10; forkhead/winged-helix transcription factor; trinucleotide repeat-containing gene 10 protein; SPCH1; TNRC10; DKFZp686H1726
• Gene ID: 93986
• mRNA Refseq: NM_001172766
• Protein Refseq: NP_001166237
• MIM: 605317
• UniProt ID: O15409