| Description : |
This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
144.4 kDa |
| AA Sequence : |
MDVFSFVKIAKLSSHRTKSSGWPPP SGTWGLSQVPPYGWEMTANRDGRDY FINHMTQAIPFDDPRLESCQIIPPA PRKVEMRRDPVLGFGFVAGSEKPVV VRSVTPGGPSEGKLIPGDQIVMIND EPVSAAPRERVIDLVRSCKESILLT VIQPYPSPKSAFISAAKKARLKSNP VKVRFSEEVIINGQVSETVKDNSLL FMPNVLKVYLENGQTKSFRFDCSTS IKDVILTLQEKLSIKGIEHFSLMLE QRTEGAGTKLLLLHEQETLTQVTQR PSSHKMRCLFRISFVPKDPIDLLRR DPVAFEYLYVQSCNDVVQERFGPEL KYDIALRLAALQMYIATVTTKQTQK ISLKYIEKEWGLETFLPSAVLQSMK EKNIKKALSHLVKANQNLVPPGKKL SALQAKVHYLKFLSDLRLYGGRVFK ATLVQAEKRSEVTLLVGPRYGISHV INTKTNLVALLADFSHVNRIEMFSE EESLVRVELHVLDVKPITLLMESSD AMNLACLTAGYYRLLVDSRRSIFNM ANKKNTATQETGPENKGKHNLLGPD WNCIPQMTTFIGEGEQEAQITYIDS KQKTVEITDSTMCPKEHRHLYIDNA YSSDGLNQQLSQPGEAPCEADYRSL AQRSLLTLSGPETLKKAQESPRGAK VSFIFGDFALDDGISPPTLGYETLL DEGPEMLEKQRNLYIGSANDMKGLD LTPEAEGIQFVENSVYANIGDVKSF QAAEGIEEPLLHDICYAENTDDAED EDEVSCEEDLVVGEMNQPAILNLSG SSDDIIDLTSLPPPEGDDNEDDFLL RSLNMAIAAPPPGFRDSSDEEDSQS QAASFPEDKEKGSSLQNDEIPVSLI DAVPTSAEGKCEKGLDNAVVSTLGA LEALSVSEEQQTSDNSGVAILRAYS PESSSDSGNETNSSEMTESSELATA QKQSENLSRMFLATHEGYHPLAEEQ TEFPASKTPAGGLPPKSSHALAARP ATDLPPKVVPSKQLLHSDHMEMEPE TMETKSVTDYFSKLHMGSVAYSCTS KRKSKLADGEGKAPPNGNTTGKKQQ GTKTAEMEEEASGKFGTVSSRDSQH LSTFNLERTAFRKDSQRWYVATEGG MAEKSGLEAATGKTFPRASGLGARE AEGKEEGAPDGETSDGSGLGQGDRF LTDVTCASSAKDLDNPEDADSSTCD HPSKLPEADESVARLCDYHLAKRMS SLQSEGHFSLQSSQGSSVDAGCGTG SSGSACATPVESPLCPSLGKHLIPD ASGKGVNYIPSEERAPGLPNHGATF KELHPQTEGMCPRMTVPALHTAINT EPLFGTLRDGCHRLPKIKETTVTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
