Recombinant Human FRS2 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | FRS2-3091H |
| Product Overview : | FRS2 MS Standard C13 and N15-labeled recombinant protein (NP_006645) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 57.5 kDa |
| AA Sequence : | MGSCCSCPDK DTVPDNHRNK FKVINVDDDG NELGSGIMEL TDTELILYTR KRDSVKWHYL CLRRYGYDSN LFSFESGRRC QTGQGIFAFK CARAEELFNM LQEIMQNNSI NVVEEPVVER NNHQTELEVP RTPRTPTTPG FAAQNLPNGY PRYPSFGDAS SHPSSRHPSV GSARLPSVGE ESTHPLLVAE EQVHTYVNTT GVQEERKNRT SVHVPLEARV SNAESSTPKE EPSSIEDRDP QILLEPEGVK FVLGPTPVQK QLMEKEKLEQ LGRDQVSGSG ANNTEWDTGY DSDERRDAPS VNKLVYENIN GLSIPSASGV RRGRLTSTST SDTQNINNSA QRRTALLNYE NLPSLPPVWE ARKLSRDEDD NLGPKTPSLN GYHNNLDPMH NYVNTENVTV PASAHKIEYS RRRDCTPTVF NFDIRRPSLE HRQLNYIQVD LEGGSDSDNP QTPKTPTTPL PQTPTRRTEL YAVIDIERTA AMSNLQKALP RDDGTSRKTR HNSTDLPMLA WKTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | FRS2 fibroblast growth factor receptor substrate 2 [ Homo sapiens (human) ] |
| Official Symbol : | FRS2 |
| Synonyms : | FRS2; fibroblast growth factor receptor substrate 2; FRS2A; FRS2alpha; SNT 1; SNT1; FGFR substrate 2; FGFR signalling adaptor; FGFR-signaling adaptor SNT; suc1-associated neurotrophic factor target 1; SNT; SNT-1; |
| Gene ID : | 10818 |
| mRNA Refseq : | NM_006654 |
| Protein Refseq : | NP_006645 |
| MIM : | 607743 |
| UniProt ID : | Q8WU20 |
◆ Recombinant Protein
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| Frs2-191M | Recombinant Mouse Frs2 Protein, His-tagged | +Inquiry |
| Frs2-3087M | Recombinant Mouse Frs2 Protein, Myc/DDK-tagged | +Inquiry |
| FRS2-4506H | Recombinant Human FRS2 Protein, GST-tagged | +Inquiry |
| FRS2-6048M | Recombinant Mouse FRS2 Protein | +Inquiry |
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◆ Lysates
| FRS2-6134HCL | Recombinant Human FRS2 293 Cell Lysate | +Inquiry |
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