Recombinant Human FRZB, His-tagged

• Cat.No.: FRZB-13010H
• Product Overview: Recombinant Human FRZB protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 27-325a.a.
• Description: The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FRZB frizzled-related protein [ Homo sapiens ]
• Official Symbol: FRZB
• Synonyms: FRZB; frizzled-related protein; secreted frizzled-related protein 3; FRE; FRITZ; FRP 3; FRZB 1; FRZB PEN; FRZB1; FZRB; hFIZ; SFRP3; SRFP3; sFRP-3; frezzled; frizzled homolog-related; frizzled-related protein 1; OS1; FRP-3; FRZB-1; FRZB-PEN
• Gene ID: 2487
• mRNA Refseq: NM_001463
• Protein Refseq: NP_001454
• MIM: 605083
• UniProt ID: Q92765
• Chromosome Location: 2qter
• Pathway: Adipogenesis, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem
• Function: PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; Wnt-protein binding