Active Recombinant Human FSCN1 Protein
Cat.No. : | FSCN1-872H |
Product Overview : | Recombinant Human FSCN1 was produced in E. coli. |
- Specification
- Gene Information
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Description : | This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. |
Source : | E. coli |
Species : | Human |
Form : | 150mM NaCl, 20mM Hepes pH 7.4, 1mM DTT and 5% sucrose, when reconstituted with 50µl ultrapure water to obtain a 1 mg/ml solution. |
Bio-activity : | Bundling activity: 2µM Atto565-Actin (Cat.#:8162-01) was incubated with Fascin at a molar ratio of 1:10 and 1:4.1 to verify bundling by fluorecence microscopy. All proteins were used as supplied, i.e. without dialysis. The actin stock solution was pre-spun 15min, 15.000xg, 4 centigrade. |
Molecular Mass : | 55kDa |
Purity : | Purity: >99% by scanning densitometry from Coomassie G-250 stained SDS-Gels. Purification notes: Fascin protein was amplified from human macrophage cDNA and expressed as a GST-tag fusion protein in E. coli. After purification by GST-Agarose and subsequent GST-tag cleavage, the pure protein was yielded by gel filtration chromatography. |
Storage : | Fascin is stored at –70 centigrade upon arrival will be stable in performance for at least 6 months from the date of purchase. The solubilized protein is kept on ice and should be stored at -20 centigrade in glycerol or CryoProtect. Avoid repeated freeze / thaw cycles. |
Shipping : | At ambient temperature. Upon delivery store at -70 centigrade. |
Gene Name : | FSCN1 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) [ Homo sapiens ] |
Official Symbol : | FSCN1 |
Synonyms : | FSCN1; fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus); singed (Drosophila) like (sea urchin fascin homolog like) , SNL; fascin; actin bundling protein; FLJ38511; p55; Singed; drosophila; homolog like; 55 kDa actin-bundling protein; singed-like (fascin homolog, sea urchin); HSN; SNL; FAN1; FLJ43305; |
Gene ID : | 6624 |
mRNA Refseq : | NM_003088 |
Protein Refseq : | NP_003079 |
MIM : | 602689 |
UniProt ID : | Q16658 |
Products Types
◆ Recombinant Protein | ||
FSCN1-4511H | Recombinant Human FSCN1 Protein, GST-tagged | +Inquiry |
FSCN1-165H | Recombinant Human FSCN1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Fscn1-1017M | Recombinant Mouse Fscn1 Protein, MYC/DDK-tagged | +Inquiry |
FSCN1-3370M | Recombinant Mouse FSCN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FSCN1-28387TH | Recombinant Human FSCN1, His-tagged | +Inquiry |
◆ Lysates | ||
FSCN1-6133HCL | Recombinant Human FSCN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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