Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human FSCN1 Protein

Cat.No. : FSCN1-872H
Product Overview : Recombinant Human FSCN1 was produced in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
Source : E. coli
Species : Human
Form : 150mM NaCl, 20mM Hepes pH 7.4, 1mM DTT and 5% sucrose, when reconstituted with 50µl ultrapure water to obtain a 1 mg/ml solution.
Bio-activity : Bundling activity: 2µM Atto565-Actin (Cat.#:8162-01) was incubated with Fascin at a molar ratio of 1:10 and 1:4.1 to verify bundling by fluorecence microscopy. All proteins were used as supplied, i.e. without dialysis. The actin stock solution was pre-spun 15min, 15.000xg, 4 centigrade.
Molecular Mass : 55kDa
Purity : Purity: >99% by scanning densitometry from Coomassie G-250 stained SDS-Gels.
Purification notes: Fascin protein was amplified from human macrophage cDNA and expressed as a GST-tag fusion protein in E. coli. After purification by GST-Agarose and subsequent GST-tag cleavage, the pure protein was yielded by gel filtration chromatography.
Storage : Fascin is stored at –70 centigrade upon arrival will be stable in performance for at least 6 months from the date of purchase. The solubilized protein is kept on ice and should be stored at -20 centigrade in glycerol or CryoProtect. Avoid repeated freeze / thaw cycles.
Shipping : At ambient temperature. Upon delivery store at -70 centigrade.
Gene Name : FSCN1 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) [ Homo sapiens ]
Official Symbol : FSCN1
Synonyms : FSCN1; fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus); singed (Drosophila) like (sea urchin fascin homolog like) , SNL; fascin; actin bundling protein; FLJ38511; p55; Singed; drosophila; homolog like; 55 kDa actin-bundling protein; singed-like (fascin homolog, sea urchin); HSN; SNL; FAN1; FLJ43305;
Gene ID : 6624
mRNA Refseq : NM_003088
Protein Refseq : NP_003079
MIM : 602689
UniProt ID : Q16658

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All FSCN1 Products

Required fields are marked with *

My Review for All FSCN1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends