Recombinant Human FSCN2 Protein, GST-tagged

• Cat.No.: FSCN2-4512H
• Product Overview: Human FSCN2 full-length ORF ( ADR83183.1, 1 a.a. - 492 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 54.2 kDa
• AA Sequence: MPTNGLHQVLKIQFGLVNDTDRYLT AESFGFKVNASAPSLKRKQTWVLEP DPGQGTAVLLRSSHLGRYLSAEEDG RVACEAEQPGRDCRFLVLPQPDGRW VLRSEPHGRFFGGTEDQLSCFATAV SPAELWTVHLAIHPQAHLLSVSRRR YVHLCPREDEMAADGDKPWGVDALL TLIFRSRRYCLKSCDSRYLRSDGRL VWEPEPRACYTLEFKAGKLAFKDCD GHYLAPVGPAGTLKAGRNTRPGKDE LFDLEESHPQVVLVAANHRYVSVRQ GVNVSANQDDELDHETFLMQIDQET KKCTFYSSTGGYWTLVTHGGIHATA TQVSANTMFEMEWRGRRVALKASNG RYVCMKKNGQLAAISDFVGKDEEFT LKLINRPILVLRGLDGFVCHHRGSN QLDTNRSVYDVFHLSFSDGAYRIRG RDGGFWYTGSHGSVCSDGERAEDFV FEFRERGRLAIRARSGKYLRGGASG LLRADADAPAGTALWEY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FSCN2 fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) [ Homo sapiens ]
• Official Symbol: FSCN2
• Synonyms: FSCN2; fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus); fascin (Strongylocentrotus purpuratus) homolog 2 (actin bundling protein, retinal); fascin-2; RFSN; RP30
• Gene ID: 25794
• mRNA Refseq: NM_001077182
• Protein Refseq: NP_001070650
• MIM: 607643
• UniProt ID: O14926