Recombinant Human FYB Protein, GST-tagged

• Cat.No.: FYB-4583H
• Product Overview: Human FYB full-length ORF ( ADR83276.1, 1 a.a. - 829 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 91.2 kDa
• AA Sequence: MAKYNTGGNPTEDVSVNSRPFRVTG PNSSSGIQARKNLFNNQGNASPPAG PSNVPKFGSPKPPVAVKPSSEEKPD KEPKPPFLKPTGAGQRFGTPASLTT RDPEAKVGFLKPVGPKPINLPKEDS KPTFPWPPGNKPSLHSVNQDHDLKP LGPKSGPTPPTSENEQKQAFPKLTG VKGKFMSASQDLEPKPLFPKPAFGQ KPPLSTENSHEDESPMKNVSSSKGS PAPLGVRSKSGPLKPAREDSENKDH AGEISSLPFPGVVLKPAASRGGPGL SKNGEEKKEDRKIDAAKNTFQSKIN QEELASGTPPARFPKAPSKLTVGGP WGQSQEKEKGDKNSATPKQKPLPPL FTLGPPPPKPNRPPNVDLTKFHKTS SGNSTSKGQTSYSTTSLPPPPPSHP ASQPPLPASHPSQPPVPSLPPRNIK PPFDLKSPVNEDNQDGVTHSDGAGN LDEEQDSEGETYEDIEASKEREKKR EKEEKKRLELEKKEQKEKEKKEQEI KKKFKLTGPIQVIHLAKACCDVKGG KNELSFKQGEQIEIIRITDNPEGKW LGRTARGSYGYIKTTAVEIDYDSLK LKKDSLGAPSRPIEDDQEVYDDVAE QDDISSHSQSGSGGIFPPPPDDDIY DGIEEEDADDGSTLQVQEKSNTWSW GILKMLKGKDDRKKSIREKPKVSDS DNNEGSSFPAPPKQLDMGDEVYDDV DTSDFPVSSAEMSQGTNFGKAKTEE KDLKKLKKQEKEEKDFRKKFKYDGE IRVLYSTKVTTSITSKKWGTRDLQV KPGESLEVIQTTDDTKVLCRNEEGK YGYVLRSYLADNDGEIYDDIADGCI YDND
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FYB FYN binding protein [ Homo sapiens ]
• Official Symbol: FYB
• Synonyms: FYB; FYN binding protein; FYN binding protein (FYB 120/130); FYN-binding protein; FYB 120/130; SLAP 130; p120/p130; FYB-120/130; FYN-T-binding protein; SLP-76-associated phosphoprotein; adhesion and degranulation-promoting adaptor protein; ADAP; PRO0823; SLAP-130
• Gene ID: 2533
• mRNA Refseq: NM_001243093
• Protein Refseq: NP_001230022
• MIM: 602731
• UniProt ID: O15117