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Recombinant Human GAB3 Protein, GST-tagged

Cat.No. : GAB3-4621H
Product Overview : Human GAB3 full-length ORF ( NP_542179.1, 1 a.a. - 586 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 92 kDa
AA Sequence : MSAGDAVCTGWLVKSPPERKLQRYA WRKRWFVLRRGRMSGNPDVLEYYRN KHSSKPIRVIDLSECAVWKHVGPSF VRKEFQNNFVFIVKTTSRTFYLVAK TEQEMQVWVHSISQVCNLGHLEDGA DSMESLSYTPSSLQPSSASSLLTAH AASSSLPRDDPNTNAVATEETRSES ELLFLPDYLVLSNCETGRLHHTSLP TRCDSWSNSDRSLEQASFDDVFVDC LQPLPSSHLVHPSCHGSGAQEVPSS RPQAALIWSREINGPPRDHLSSSPL LESSLSSTIQVDKNQGSLPCGAKEL DIMSNTPPPRPPKPSHLSERRQEEW STHSGSKKPECTLVPRRISLSGLDN MRTWKADVEGQSLRHRDKRLSLNLP CRFSPMYPTASASIEDSYVPMSPQA GASGLGPHCSPDDYIPMNSGSISSP LPELPANLEPPPVNRDLKPQRKSRP PPLDLRNLSIIREHASLTRTRTVPC SRTSFLSPERNGINSARFFANPVSR EDEESYIEMEEHRTASSLSSGALTW TKKFSLDYLALDFNSASPAPMQQKL LLSEEQRVDYVQVDEQKTQALQSTK QEWTDERQSKV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GAB3 GRB2 associated binding protein 3 [ Homo sapiens (human) ]
Official Symbol : GAB3
Synonyms : GAB3; GRB2 associated binding protein 3; GRB2-associated-binding protein 3; DOS/Gab family member 3; GRB2-associated binder 3; Gab3 scaffolding protein; growth factor receptor bound protein 2-associated protein 3; GRB2 Associated Binding Protein 3; Growth Factor Receptor Bound Protein 2-Associated Protein 3; Gab3 Scaffolding Protein; GRB2-Associated Binder 3; DOS/Gab Family Member 3
Gene ID : 139716
mRNA Refseq : NM_001081573
Protein Refseq : NP_001075042
MIM : 300482
UniProt ID : Q8WWW8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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