Recombinant Human GABPA Protein, GST-tagged

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Recombinant Human GABPA Protein, GST-tagged

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Cat.No. : GABPA-4631H
Product Overview : Human GABPA full-length ORF ( AAH35031, 1 a.a. - 454 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 75.68 kDa
AA Sequence : MTKREAEELI EIEIDGTEKA ECTEESIVEQ TYAPAECVSQ AIDINEPIGN LKKLLEPRLQ CSLDAHEICL QDIQLDPERS LFDQGVKTDG TVQLSVQVIS YQGIEPKLNI LEIVKPADTV EVVIDPDAHH AESEAHLVEE AQVITLDGTK HITTISDETS EQVTRWAAAL EGYRKEQERL GIPYDPIQWS TDQVLHWVVW VMKEFSMTDI DLTTLNISGR ELCSLNQEDF FQRVPRGEIL WSHLELLRKY VLASQEQQMN EIVTIDQPVQ IIPASVQSAT PTTIKVINSS AKAAKVQRAP RISGEDRSSP GNRTGNNGQI QLWQFLLELL TDKDARDCIS WVGDEGEFKL NQPELVAQKW GQRKNKPTMN YEKLSRALRY YYDGDMICKV QGKRFVYKFV CDLKTLIGYS AAELNRLVTE CEQKKLAKMQ LHGIAQPVTA VALSTASLQT EKDN
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : GABPA GA binding protein transcription factor, alpha subunit 60kDa [ Homo sapiens ]
Official Symbol : GABPA
Synonyms : GABPA; GA binding protein transcription factor, alpha subunit 60kDa; GA binding protein transcription factor, alpha subunit (60kD); GA-binding protein alpha chain; E4TF1 60; E4TF1A; human nuclear respiratory factor 2 subunit alpha; NFT2; NRF2; NRF2A; nuclear respiratory factor 2 alpha subunit; GABP subunit alpha; transcription factor E4TF1-60; nuclear respiratory factor 2 subunit alpha; human nuclear respiratory factor-2 subunit alpha; GA binding protein transcription factor alpha subunit 60kDa; E4TF1-60; RCH04A07;
Gene ID : 2551
mRNA Refseq : NM_001197297
Protein Refseq : NP_001184226
MIM : 600609
UniProt ID : Q06546

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