Recombinant Human GABPA Protein, His-tagged

• Cat.No.: GABPA-554H
• Product Overview: Recombinant Human GABPA(Ala168~Thr314) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 20.4kDa
• Protein length: Ala168~Thr314
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 98%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: GABPA GA binding protein transcription factor, alpha subunit 60kDa [ Homo sapiens ]
• Official Symbol: GABPA
• Synonyms: GABPA; GA binding protein transcription factor, alpha subunit 60kDa; GA binding protein transcription factor, alpha subunit (60kD); GA-binding protein alpha chain; E4TF1 60; E4TF1A; human nuclear respiratory factor 2 subunit alpha; NFT2; NRF2; NRF2A; nuclear respiratory factor 2 alpha subunit; GABP subunit alpha; transcription factor E4TF1-60; nuclear respiratory factor 2 subunit alpha; human nuclear respiratory factor-2 subunit alpha; GA binding protein transcription factor alpha subunit 60kDa; E4TF1-60; RCH04A07
• Gene ID: 2551
• mRNA Refseq: NM_001197297
• Protein Refseq: NP_001184226
• MIM: 600609
• UniProt ID: Q06546