Recombinant Human GABRA3, GST-tagged

• Cat.No.: GABRA3-13093H
• Product Overview: Recombinant Human GABRA3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 24-282a.a.
• Description: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 [ Homo sapiens ]
• Official Symbol: GABRA3
• Synonyms: GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3; gamma-aminobutyric acid receptor subunit alpha-3; GABA(A) receptor; alpha 3; GABA(A) receptor, alpha 3; GABA(A) receptor subunit alpha-3; gamma-animobutyric acid (GABA) A receptor, alpha 3; MGC33793
• Gene ID: 2556
• mRNA Refseq: NM_000808
• Protein Refseq: NP_000799
• MIM: 305660
• UniProt ID: P34903
• Chromosome Location: Xq28
• Pathway: GABA A receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem; GABAergic synapse, organism-specific biosystem; GABAergic synapse, conserved biosystem; Ion channel transport, organism-specific biosystem; Ligand-gated ion channel transport, organism-specific biosystem; Morphine addiction, organism-specific biosystem
• Function: GABA-A receptor activity; benzodiazepine receptor activity; chloride channel activity; extracellular ligand-gated ion channel activity; ion channel activity; receptor activity