Recombinant Human GADD45A Protein, MYC/DDK-tagged

• Cat.No.: GADD45A-941H
• Product Overview: Recombinant human GADD45A protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 18.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: growth arrest and DNA damage inducible alpha[ Homo sapiens ]
• Official Symbol: GADD45A
• Synonyms: DDIT1; GADD45
• Gene ID: 1647
• mRNA Refseq: NM_001199741.1
• Protein Refseq: NP_001915
• MIM: 126335
• UniProt ID: P24522