Recombinant Human GALNT4 Protein, GST-tagged

• Cat.No.: GALNT4-4703H
• Product Overview: Human GALNT4 full-length ORF ( AAH36390, 40 a.a. - 578 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 85.03 kDa
• AA Sequence: RARELGSRRLSGLQKNTEDLSRPLY KKPPADSRALGEWGKASKLQLNEDE LKQQEELIERYAINIYLSDRISLHR HIEDKRMYECKSQKFNYRTLPTTSV IIAFYNEAWSTLLRTIHSVLETSPA VLLKEIILVDDLSDRVYLKTQLETY ISNLDRVRLIRTNKREGLVRARLIG ATFATGDVLTFLDCHCECNSGWLEP LLERIGRDETAVVCPVIDTIDWNTF EFYMQIGEPMIGGFDWRLTFQWHSV PKQERDRRISRIDPIRSPTMAGGLF AVSKKYFQYLGTYDTGMEVWGGENL ELSFRVWQCGGKLEIHPCSHVGHVF PKRAPYARPNFLQNTARAAEVWMDE YKEHFYNRNPPARKEAYGDISERKL LRERLRCKSFDWYLKNVFPNLHVPE DRPGWHGAIRSRGISSECLDYNSPD NNPTGANLSLFGCHGQGGNQFFEYT SNKEIRFNSVTELCAEVPEQKNYVG MQNCPKDGFPVPANIIWHFKEDGTI FHPHSGLCLSAYRTPEGRPDVQMRT CDALDKNQIWSFEK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GALNT4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) [ Homo sapiens ]
• Official Symbol: GALNT4
• Synonyms: GALNT4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4); polypeptide N-acetylgalactosaminyltransferase 4; GalNAc T4; pp-GaNTase 4; polypeptide GalNAc transferase 4; protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4; GALNACT4; GALNAC-T4; FLJ93314
• Gene ID: 8693
• mRNA Refseq: NM_003774
• Protein Refseq: NP_003765
• MIM: 603565
• UniProt ID: Q8N4A0