Recombinant Human GALNT4 Protein, GST-tagged

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Recombinant Human GALNT4 Protein, GST-tagged

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Cat.No. : GALNT4-4703H
Product Overview : Human GALNT4 full-length ORF ( AAH36390, 40 a.a. - 578 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 85.03 kDa
AA Sequence : RARELGSRRL SGLQKNTEDL SRPLYKKPPA DSRALGEWGK ASKLQLNEDE LKQQEELIER YAINIYLSDR ISLHRHIEDK RMYECKSQKF NYRTLPTTSV IIAFYNEAWS TLLRTIHSVL ETSPAVLLKE IILVDDLSDR VYLKTQLETY ISNLDRVRLI RTNKREGLVR ARLIGATFAT GDVLTFLDCH CECNSGWLEP LLERIGRDET AVVCPVIDTI DWNTFEFYMQ IGEPMIGGFD WRLTFQWHSV PKQERDRRIS RIDPIRSPTM AGGLFAVSKK YFQYLGTYDT GMEVWGGENL ELSFRVWQCG GKLEIHPCSH VGHVFPKRAP YARPNFLQNT ARAAEVWMDE YKEHFYNRNP PARKEAYGDI SERKLLRERL RCKSFDWYLK NVFPNLHVPE DRPGWHGAIR SRGISSECLD YNSPDNNPTG ANLSLFGCHG QGGNQFFEYT SNKEIRFNSV TELCAEVPEQ KNYVGMQNCP KDGFPVPANI IWHFKEDGTI FHPHSGLCLS AYRTPEGRPD VQMRTCDALD KNQIWSFEK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : GALNT4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) [ Homo sapiens ]
Official Symbol : GALNT4
Synonyms : GALNT4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4); polypeptide N-acetylgalactosaminyltransferase 4; GalNAc T4; pp-GaNTase 4; polypeptide GalNAc transferase 4; protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4; GALNACT4; GALNAC-T4; FLJ93314;
Gene ID : 8693
mRNA Refseq : NM_003774
Protein Refseq : NP_003765
MIM : 603565
UniProt ID : Q8N4A0

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