Recombinant Human GANAB Protein, GST-tagged

• Cat.No.: GANAB-4719H
• Product Overview: Human GANAB full-length ORF ( NP_938148.1, 1 a.a. - 944 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 133.3 kDa
• AA Sequence: MAAVAAVAARRRRSWASLVLAFLGV CLGITLAVDRSNFKTCEESSFCKRQ RSIRPGLSPYRALLDSLQLGPDSLT VHLIHEVTKVLLVLELQGLQKNMTR FRIDELEPRRPRYRVPDVLVADPPI ARLSVSGRDENSVELTMAEGPYKII LTARPFRLDLLEDRSLLLSVNARGL LEFEHQRAPRVSQGSKDPAEGDGAQ PEETPRDGDKPEETQGKAEKDEPGA WEETFKTHSDSKPYGPMSVGLDFSL PGMEHVYGIPEHADNLRLKVTEGGE PYRLYNLDVFQYELYNPMALYGSVP VLLAHNPHRDLGIFWLNAAETWVDI SSNTAGKTLFGKMMDYLQGSGETPQ TDVRWMSETGIIDVFLLLGPSISDV FRQYASLTGTQALPPLFSLGYHQSR WNYRDEADVLEVDQGFDDHNLPCDV IWLDIEHADGKRYFTWDPSRFPQPR TMLERLASKRRKLVAIVDPHIKVDS GYRVHEELRNLGLYVKTRDGSDYEG WCWPGSAGYPDFTNPTMRAWWANMF SYDNYEGSAPNLFVWNDMNEPSVFN GPEVTMLKDAQHYGGWEHRDVHNIY GLYVHMATADGLRQRSGGMERPFVL ARAFFAGSQRFGAVWTGDNTAEWDH LKISIPMCLSLGLVGLSFCGADVGG FFKNPEPELLVRWYQMGAYQPFFRA HAHLDTGRREPWLLPSQHNDIIRDA LGQRYSLLPFWYTLLYQAHREGIPV MRPLWVQYPQDVTTFNIDDQYLLGD ALLVHPVSDSGAHGVQVYLPGQGEV WYDIQSYQKHHGPQTLYLPVTLSSI PVFQRGGTIVPRWMRVRRSSECMKD DPITLFVALSPQGTAQGELFLDDGH TFNYQTRQEFLLRRFSFSGNTLVSS SADPEGHFETPIWIERVVIIGAGKP AAVVLQTKGSPESRLSFQHDPETSV LVLRKPGINVASDWSIHLR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GANAB glucosidase, alpha; neutral AB [ Homo sapiens ]
• Official Symbol: GANAB
• Synonyms: GANAB; glucosidase, alpha; neutral AB; neutral alpha-glucosidase AB; G2AN; GluII; KIAA0088; alpha-glucosidase 2; glucosidase II subunit alpha; alpha glucosidase II alpha subunit; GLUII
• Gene ID: 23193
• mRNA Refseq: NM_198334
• Protein Refseq: NP_938148
• MIM: 104160
• UniProt ID: Q14697