| Description : |
This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
106.7 kDa |
| AA Sequence : |
MAAVAAVAARRRRSWASLVLAFLGV CLGITLAVDRSNFKTCEESSFCKRQ RSIRPGLSPYRALLDSLQLGPDSLT VHLIHEVTKVLLVLELQGLQKNMTR FRIDELEPRRPRYRVPDVLVADPPI ARLSVSGRDENSVELTMAEGPYKII LTARPFRLDLLEDRSLLLSVNARGL LEFEHQRAPRVSQGSKDPAEGDGAQ PEETPRDGDKPEETQGKAEKDEPGA WEETFKTHSDSKPYGPMSVGLDFSL PGMEHVYGIPEHADNLRLKVTEGGE PYRLYNLDVFQYELYNPMALYGSVP VLLAHNPHRDLGIFWLNAAETWVDI SSNTAGKTLFGKMMDYLQGSGETPQ TDVRWMSETGIIDVFLLLGPSISDV FRQYASLTGTQALPPLFSLGYHQSR WNYRDEADVLEVDQGFDDHNLPCDV IWLDIEHADGKRYFTWDPSRFPQPR TMLERLASKRRKLVAIVDPHIKVDS GYRVHEELRNLGLYVKTRDGSDYEG WCWPGSAGYPDFTNPTMRAWWANMF SYDNYEGSAPNLFVWNDMNEPSVFN GPEVTMLKDAQHYGGWEHRDVHNIY GLYVHMATADGLRQRSGGMERPFVL ARAFFAGSQRFGAVWTGDNTAEWDH LKISIPMCLSLGLVGLSFCGADVGG FFKNPEPELLVRWYQMGAYQPFFRA HAHLDTGRREPWLLPSQHNDIIRDA LGQRYSLLPFWYTLLYQAHREGIPV MRPLWVQYPQDVTTFNIDDQYLLGD ALLVHPVSDSGAHGVQVYLPGQGEV WYDIQSYQKHHGPQTLYLPVTLSSI PVFQRGGTIVPRWMRVRRSSECMKD DPITLFVALSPQGTAQGELFLDDGH TFNYQTRQEFLLRRFSFSGNTLVSS SADPEGHFETPIWIERVVIIGAGKP AAVVLQTKGSPESRLSFQHDPETSV LVLRKPGINVASDWSIHLRTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
