Recombinant Human GATAD2B Protein, GST-tagged

• Cat.No.: GATAD2B-4758H
• Product Overview: Human GATAD2B full-length ORF (BAG52906.1, 1 a.a. - 593 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a zinc finger protein transcriptional repressor. The encoded protein is part of the methyl-CpG-binding protein-1 complex, which represses gene expression by deacetylating methylated nucleosomes. Mutations in this gene are linked to intellectual disability and dysmorphic features associated with mental retardation. [provided by RefSeq, Jun 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 91.7 kDa
• AA Sequence: MDRMTEDALRLNLLKRSLDPADERD DVLAKRLKMEGHEAMERLKMLALLK RKDLANLEVPHELPTKQDGSGVKGY EEKLNGNLRPHGDNRTAGRPGKENI NDEPVDMSARRSEPERGRLTPSPDI IVLSDNEASSPRSSSRMEERLKAAN LEMFKGKGIEERQQLIKQLRDELRL EEARLVLLKKLRQSQLQKENVVRKT PVVQNAASIVQPSPAHVGQQGLSKL PSRPGAQGVEPQNLRTLQGHSVIRS ATNTTLPHMLMSQRVIAPNPAQLQG QRGPPKPGLVRTTTPNMNPAINYQP QSSSSVPCQRTTSSAIYMNLASHIQ PGAVNRVSSPLPSPSAMTDAANSQA AAKLALRKQLEKTLLEIPPPKPPAP LLHFLPSAANSEFIYMVGLEEVVQS VIDSQGKSCASLLRVEPFVCAQCRT DFTPHWKQEKNGKILCEQCMTSNQK KALKAEHTNRLKNAFVKALQQEQEI EQRLQQQAALSPTTAPAVSSVSKQE TIMRHHTLRQAPQPQSSLQRGIPTS ARSMLSNFAQAPQLSVPGGLLGMPG VNIAYLNTGIGGHKGPSLADRQREY LLDMIPPRSISQSISGQK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GATAD2B GATA zinc finger domain containing 2B [ Homo sapiens ]
• Official Symbol: GATAD2B
• Synonyms: GATAD2B; GATA zinc finger domain containing 2B; transcriptional repressor p66-beta; P66beta; transcription repressor p66 beta component of the MeCP1 complex; p66/p68; GATA zinc finger domain-containing protein 2B; FLJ37346; KIAA1150; RP11-216N14.6; MGC138257; MGC138285
• Gene ID: 57459
• mRNA Refseq: NM_020699
• Protein Refseq: NP_065750
• MIM: 614998
• UniProt ID: Q8WXI9