Recombinant Human GCG Protein, Myc/DDK-tagged, C13 and N15-labeled GCG-1451H

Recombinant Human GCG Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	GCG-1451H
Product Overview :	GCG MS Standard C13 and N15-labeled recombinant protein (NP_002045) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	20.9 kDa
AA Sequence :	MKSIYFVAGL FVMLVQGSWQ RSLQDTEEKS RSFSASQADP LSDPDQMNED KRHSQGTFTS DYSKYLDSRR AQDFVQWLMN TKRNRNNIAK RHDEFERHAE GTFTSDVSSY LEGQAAKEFI AWLVKGRGRR DFPEEVAIVE ELGRRHADGS FSDEMNTILD NLAARDFINW LIQTKITDRK TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	GCG glucagon [ Homo sapiens (human) ]
Official Symbol :	GCG
Synonyms :	GCG; glucagon; glicentin related polypeptide; GLP1; GLP2; glucagon like peptide 1; glucagon like peptide 2; GRPP; glucagon-like peptide 1; glucagon-like peptide 2; glicentin-related polypeptide;
Gene ID :	2641
mRNA Refseq :	NM_002054
Protein Refseq :	NP_002045
MIM :	138030
UniProt ID :	P01275