Recombinant Human GDF15 protein(Ala197-Ile308), hFc-tagged
Cat.No. : | GDF15-204H |
Product Overview : | Recombinant Human GDF15 (NP_004855.2) (Ala 197-Ile 308) was expressed in HEK293 with the fused Fc region of Human IgG1 at the N-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | N-hFc |
Protein length : | Ala197-Ile308 |
Form : | Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.8. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human Fc/GDF15 is a disulfide-linked homodimeric protein. The reduced monomer consists of 370 amino acids and has a predicted molecular mass of 40.6 kDa. rhGDF15/Fc monomer migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | GDF15 growth differentiation factor 15 [ Homo sapiens ] |
Official Symbol : | GDF15 |
Synonyms : | GDF15; growth differentiation factor 15; growth/differentiation factor 15; MIC 1; MIC1; NAG 1; PDF; PLAB; prostate differentiation factor; PTGFB; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; macrophage inhibitory cytokine 1; placental bone morphogenetic protein; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; MIC-1; NAG-1; GDF-15; |
Gene ID : | 9518 |
mRNA Refseq : | NM_004864 |
Protein Refseq : | NP_004855 |
MIM : | 605312 |
UniProt ID : | Q99988 |
Products Types
◆ Recombinant Protein | ||
GDF15-20H | Recombinant Human GDF15 protein(Ala197-Ile308), His-tagged | +Inquiry |
GDF15-106H | Recombinant Human GDF15 Protein | +Inquiry |
GDF15-285H | Recombinant Human GDF15 protein, His-tagged | +Inquiry |
GDF15-0067H | Recombinant Human GDF15 Protein | +Inquiry |
GDF15-338H | Recombinant Human GDF15 Protein, His tagged | +Inquiry |
◆ Native Protein | ||
GDF15-27680TH | Active Native Human GDF15 Protein | +Inquiry |
◆ Lysates | ||
GDF15-2705HCL | Recombinant Human GDF15 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGDF15 influences cardiovascular health, impacting heart failure progression and atherosclerotic processes.
GDF15 modulates inflammatory and immune responses, crucial in the context of chronic diseases.
GDF15 contributes to tissue repair and fibrosis, particularly in liver and kidney pathologies.
GDF15 affects cancer development by altering the tumor microenvironment and influencing tumor cell behavior.
Changes in GDF15 expression are linked to aging and age-related diseases, affecting various physiological processes.
GDF15 is involved in regulating energy metabolism and appetite, playing a key role in obesity and metabolic syndromes.
GDF15 is involved in cellular stress responses, influencing apoptosis and cell survival mechanisms.
Customer Reviews (3)
Write a reviewDependable protein purification, consistent and cost-effective.
Precise mass spectrometry analysis, key for proteomics research.
Great antibody validation, enhances our immunoprecipitation experiments.
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