Recombinant Human General Transcription Factor IIF, Polypeptide 2, 30kDa, His-tagged
Cat.No. : | GTF2F2-5599H |
Product Overview : | Recombinant humanGTF2F2 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | GTF2F2-5599H |
Description : | GTF2F2, also knownas TFIIF, is a general transcription initiation factor that binds to RNApolymerase II and helps to recruit it to the initiation complex incollaboration with TFIIB. It promotes transcription elongation. This subunitshows ATP-dependent DNA-helicase activity. |
Source : | E. coli |
Species : | Human |
Form : | Liquid. 20mMTris-HCl buffer (pH 8.0) containing 20% glycerol 0.2M NaCl, 1mM DTT. |
Molecular Weight : | 30.5 kDa(269aa), confirmedby MALDI-TOF (Molecular weight on SDS-PAGE will appear higher). |
Purity : | > 90% by SDS -PAGE. |
Concentration : | 0.5mg/ml (determinedby Bradford assay). |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MAERGELDLT GAKQNTGVWL VKVPKYLSQQ WAKASGRGEV GKLRIAKTQG RTEVSFTLNE DLANIHDIGGKPASVSAPRE HPFVLQSVGG QTLTVFTESS SDKLSLEGIV VQRAECRPAA SENYMRLKRL QIEESSKPVRLSQQLDKVVT TNYKPVANHQ YNIEYERKKK EDGKRARADK QHVLDMLFSA FEKHQYYNLK DLVDITKQPVVYLKEILKEI GVQNVKGIHK NTWELKPEYR HYQGEEKSD |
Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles. |
OfficialSymbol : | GTF2F2 |
Gene Name : | GTF2F2 general transcriptionfactor IIF, polypeptide 2, 30kDa [ Homo sapiens ] |
Synonyms : | GTF2F2; generaltranscription factor IIF, polypeptide 2, 30kDa; BTF4; RAP30; TF2F2;TFIIF; general transcription factor IIF subunit 2; TFIIF-beta; ATP-dependenthelicase GTF2F2; transcription initiation factor RAP30; general transcriptionfactor IIF 30 kDa subunit; transcription initiation factor IIF subunit beta |
Gene ID : | 2963 |
mRNA Refseq : | NM_004128 |
Protein Refseq : | NP_004119 |
MIM : | 189969 |
UniProt ID : | P13984 |
Chromosome Location : | 13q14 |
Pathway : | Abortive elongationof HIV-1 transcript in the absence of Tat; Androgen Receptor SignalingPathway; Basal transcription factors; Eukaryotic Transcription Initiation;Formation and Maturation of mRNA Transcript; Formation of RNA Pol IIelongation complex; Gene Expression; Influenza Infection; Pausing andrecovery of HIV-1 elongation; RNA Pol II CTD phosphorylation and interactionwith CE; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening;Tat-mediated HIV-1 elongation arrest and recovery; Transcription; Viral MessengerRNA Synthesis; mRNA Splicing |
Function : | ATP binding;ATP-dependent helicase activity; DNA binding; helicase activity; hydrolaseactivity; nucleotide binding; protein binding |
Products Types
◆ Recombinant Protein | ||
GTF2F2-4446H | Recombinant Human GTF2F2 Protein, GST-tagged | +Inquiry |
Gtf2f2-3326M | Recombinant Mouse Gtf2f2 Protein, Myc/DDK-tagged | +Inquiry |
GTF2F2-1827R | Recombinant Rhesus Macaque GTF2F2 Protein, His (Fc)-Avi-tagged | +Inquiry |
GTF2F2-2006R | Recombinant Rhesus monkey GTF2F2 Protein, His-tagged | +Inquiry |
GTF2F2-1184H | Active Recombinant Human General Transcription Factor IIF, Polypeptide 2, 30kDa | +Inquiry |
◆ Lysates | ||
GTF2F2-5699HCL | Recombinant Human GTF2F2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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