Recombinant Human GET3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GET3-3520H
• Product Overview: ASNA1 MS Standard C13 and N15-labeled recombinant protein (NP_004308) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
• Molecular Mass: 38.8 kDa
• AA Sequence: MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQAKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GET3 guided entry of tail-anchored proteins factor 3, ATPase [ Homo sapiens (human) ]
• Official Symbol: GET3
• Synonyms: GET3; guided entry of tail-anchored proteins factor 3, ATPase; ARSA1; ASNA1; TRC40; ARSA-I; ASNA-I; ATPase GET3; arsA arsenite transporter, ATP-binding, homolog 1; golgi to ER traffic 3 homolog; transmembrane domain recognition complex 40 kDa ATPase subunit; EC 7.3.2.7
• Gene ID: 439
• mRNA Refseq: NM_004317
• Protein Refseq: NP_004308
• MIM: 601913
• UniProt ID: O43681