Recombinant Human GFM2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human GFM2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : GFM2-4459H
Product Overview : GFM2 MS Standard C13 and N15-labeled recombinant protein (NP_115756) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA. Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 86.2 kDa
AA Sequence : MLTNLRIFAM SHQTIPSVYI NNICCYKIRA SLKRLKPHVP LGRNCSSLPG LIGNDIKSIH SIINPPIAKI RNIGIMAHID AGKTTTTERI LYYSGYTRSL GDVDDGDTVT DFMAQERERG ITIQSAAVTF DWKGYRVNLI DTPGHVDFTL EVERCLRVLD GAVAVFDASA GVEAQTLTVW RQADKHNIPR ICFLNKMDKT GASFKYAVES IREKLKAKPL LLQLPIGEAK TFKGVVDVVM KEKLLWNCNS NDGKDFERKP LLEMNDPELL KETTEARNAL IEQVADLDDE FADLVLEEFS ENFDLLPAEK LQTAIHRVTL AQTAVPVLCG SALKNKGIQP LLDAVTMYLP SPEERNYEFL QWYKDDLCAL AFKVLHDKQR GPLVFMRIYS GTIKPQLAIH NINGNCTERI SRLLLPFADQ HVEIHSLTAG NIALTVGLKH TATGDTIVSS KSSALAAARR AEREGEKKHR QNNEAERLLL AGVEIPEPVF FCTIEPPSLS KQPDLEHALK CLQREDPSLK VRLDPDSGQT VLCGMGELHI EIIHDRIKRE YGLETYLGPL QVAYRETILN SVRATDTLDR TLGDKRHLVT VEVGARPIET SSVMPVIEYA ESINEGLLKV SQEAIENGIH SACLQGPLLG SPIQDVAITL HSLTIHPGTS TTMISACVSR CVQKALKKAD KQVLEPLMNL EVTVARDYLS PVLADLAQRR GNIQEIQTRQ DNKVVIGFVP LAGIMGYSTV LRTLTSGSAT FALELSTYQA MNPQDQNTLL NRRSGLTTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GFM2 GTP dependent ribosome recycling factor mitochondrial 2 [ Homo sapiens (human) ]
Official Symbol : GFM2
Synonyms : GFM2; G elongation factor, mitochondrial 2; ribosome-releasing factor 2, mitochondrial; EFG2; FLJ21661; MSTP027; mitochondrial elongation factor G2; elongation factor G 2, mitochondrial; mitochondrial ribosome recycling factor 2; RRF2; MRRF2; hEFG2; MST027; RRF2mt; EF-G2mt; mEF-G 2;
Gene ID : 84340
mRNA Refseq : NM_032380
Protein Refseq : NP_115756
MIM : 606544
UniProt ID : Q969S9

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