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Recombinant Human GFRA1 Protein, His-tagged

Cat.No. : GFRA1-712H
Product Overview : Recombinant human GFRA1 protein was expressed from CHO-based cell line with His-tag and purified by QMCF Technology.
  • Specification
  • Gene Information
  • Related Products
Description : Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.
Source : CHO
Species : Human
Tag : His
Form : PBS pH 7.4.
Molecular Mass : Approximately 45.9 kDa, a single non-glycosylated polypeptide chain containing 409 amino acids including C-terminal hexahistidine tag.
Storage : Store at -70 centigrade upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles.
Concentration : 0.9 mg/ml
Gene Name : GDNF family receptor alpha 1
Official Symbol : GFRA1
Synonyms : RET ligand 1,TGF-beta-related neurotrophic factor receptor 1
Gene ID : 2674
mRNA Refseq : NM_001145453.1
Protein Refseq : NP_001138925.1
MIM : 601496
UniProt ID : P56159

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any ongoing clinical trials targeting GFRA1 for neurodegenerative diseases? 05/25/2021

Yes, several clinical trials are exploring the modulation of GFRA1 for the treatment of neurodegenerative diseases.

How does GFRA1 contribute to neuroprotection? 04/25/2020

GFRA1 is involved in neuroprotection by promoting the survival and maintenance of neurons, making it a potential target for therapeutic interventions.

How does GFRA1 influence the development and function of the nervous system? 10/10/2017

GFRA1 is crucial for the development and function of the nervous system as it participates in the regulation of neuronal survival and differentiation.

Are there any therapeutic strategies targeting GFRA1 for neuroregeneration? 10/26/2016

Some therapeutic strategies aim to harness GFRA1 for promoting neuroregeneration, especially in the context of nerve injuries.

Can GFRA1 protein be a biomarker for certain neurological disorders? 07/12/2016

Research suggests that alterations in GFRA1 expression may serve as a potential biomarker for specific neurological disorders.

Customer Reviews (3)

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Reviews
03/24/2022

    With their expertise, I can navigate through experimental hurdles, optimize protocols, and ensure the seamless integration of the GFRA1 protein into my investigations.

    08/19/2020

      The GFRA1 protein showcases unparalleled quality, ensuring it surpasses expectations and satisfactorily addresses my experimental requirements.

      03/11/2020

        Their knowledgeable and responsive team stands ready to address any concerns or challenges I may encounter.

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