Active Recombinant Human GFRA3 protein, His&hFc-tagged

• Cat.No.: GFRA3-3242H
• Product Overview: Active Recombinant Human GFRA3 protein(NP_001487.2) (Met 1-Trp 382) was expressed in HEK293, fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc&His
• Protein Length: 1-382 aa
• Form: Lyophilized from sterile PBS, pH 7.5.
• Bio-activity: Measured by its ability to bind mouse ARTN in a functional ELISA.
• Molecular Mass: The recombinant human GFRa3/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 599 amino acids and predicts a molecular mass of 67.3 kDa. As a result of glycosylation, the rh GFRa3/Fc monomer migrates as an approximately 80 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1 EU/µg as determined by LAL test.
• Purity: > 80 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: GFRA3 GDNF family receptor alpha 3 [ Homo sapiens ]
• Official Symbol: GFRA3
• Synonyms: GFRA3; GDNF family receptor alpha 3; GDNF family receptor alpha-3; GFRa 3; GFR-alpha-3; GDNFR-alpha-3; GPI-linked receptor; GDNF receptor alpha-3; glial cell line-derived neurotrophic factor receptor alpha-3
• Gene ID: 2676
• mRNA Refseq: NM_001496
• Protein Refseq: NP_001487
• MIM: 605710
• UniProt ID: O60609