| Description : |
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
61.4 kDa |
| AA Sequence : |
MEPAMEPETLEARINRATNPLNKEL DWASINGFCEQLNEDFEGPPLATRL LAHKIQSPQEWEAIQALTVLETCMK SCGKRFHDEVGKFRFLNELIKVVSP KYLGSRTSEKVKNKILELLYSWTVG LPEEVKIAEAYQMLKKQGIVKSDPK LPDDTTFPLPPPRPKNVIFEDEEKS KMLARLLKSSHPEDLRAANKLIKEM VQEDQKRMEKISKRVNAIEEVNNNV KLLTEMVMSHSQGGAAAGSSEDLMK ELYQRCERMRPTLFRLASDTEDNDE ALGLSDPTPPSGPSLDGTGWNSFQS SDATEPPAPALAQAPSMESRPPAQT SLPASSGLDDLDLLGKTLLQQSLPP ESQQVRWEKQQPTPRLTLRDLQNKS SSCSSPSSSATSLLHTVSPEPPRPP QQPVPTELSLASITVPLESIKPSNI LPVTVYDQHGFRILFHFARDPLPGR SDVLVVVVSMLSTAPQPIRNIVFQS AVPKVMKVKLQPPSGTELPAFNPIV HPSAITQVLLLANPQKEKVRLRYKL TFTMGDQTYNEMGDVDQFPPPETWG SLTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
