Recombinant Human GGA3 Protein, GST-tagged

• Cat.No.: GGA3-4867H
• Product Overview: Human GGA3 full-length ORF ( AAH70044.1, 1 a.a. - 690 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 100.9 kDa
• AA Sequence: MAEAEGESLESWLNKATNPSNRQED WEYIIGFCDQINKELEGPQIAVRLL AHKIQSPQEWEALQALTYLGDRVSE KVKTKVIELLYSWTMALPEEAKIKD AYHMLKRQGIVQSDPPIPVDRTLIP SPPPRPKNPVFDDEEKSKLLAKLLK SKNPDDLQEANKLIKSMVKEDEARI QKVTKRLHTLEEVNNNVRLLSEMLL HYSQEDSSDGDRELMKELFDQCENK RRTLFKLASETEDNDNSLGDILQAS DNLSRVINSYKTIIEGQVINGEVAT LTLPDSEGNSQCSNQGTLIDLAELD TTNSLSSVLAPAPTPPSSGIPILPP PPQASGPPRSRSSSQAEATLGPSST SNALSWLDEELLCLGLADPAPNVPP KESAGNSQWHLLQREQSDLDFFSPR PGTAACGASDAPLLKPSAPSSSSSQ APLPPPFPAPVVPASVPAPSAGSSL FSTGVAPALAPKVEPAVPGHHGLAL GNSALHHLDALDQLLEEAKVTSGLV KPTTSPLIPTTTPARPLLPFSTGPG SPLFQPLSFQSQGSPPKGPELSLAS IHVPLESIKPSSALPVTAYDKNGFR ILFHFAKECPPGRPDVLVVVVSMLN TAPLPVKSIVLQAAVPKSMKVKLQP PSGTELSPFSPIQPPAAITQVMLLA NPLKEKVRLRYKLTFALGEQLSTEV GEVDQFPPVEQWGNL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 [ Homo sapiens ]
• Official Symbol: GGA3
• Synonyms: GGA3; golgi-associated, gamma adaptin ear containing, ARF binding protein 3; ADP-ribosylation factor-binding protein GGA3; KIAA0154; Golgi-localized, gamma ear-containing, ARF-binding protein 3; golgi associated, gamma adaptin ear containing, ARF binding protein 3
• Gene ID: 23163
• mRNA Refseq: NM_001172703
• Protein Refseq: NP_001166174
• MIM: 606006
• UniProt ID: Q9NZ52