"GJA8" Related Products

Recombinant Human GJA8 Protein, GST-tagged

Cat.No. : GJA8-4924H
Product Overview : Human GJA8 full-length ORF ( AAI46508.1, 1 a.a. - 433 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 74.58 kDa
AA Sequence : MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLSKASSRARSDDLTV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : GJA8 gap junction protein, alpha 8, 50kDa [ Homo sapiens ]
Official Symbol : GJA8
Synonyms : GJA8; gap junction protein, alpha 8, 50kDa; CAE, CAE1, CZP1, gap junction protein, alpha 8, 50kD (connexin 50), gap junction protein, alpha 8, 50kDa (connexin 50); gap junction alpha-8 protein; connexin 50; CX50; connexin-50; lens fiber protein MP70; cell surface glycoprotein; lens intrinsic membrane protein MP70; gap junction membrane channel protein alpha-8; CAE; CAE1; CZP1; MP70;
Gene ID : 2703
mRNA Refseq : NM_005267
Protein Refseq : NP_005258
MIM : 600897
UniProt ID : P48165

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