Recombinant Human GJB1 Protein, His&GST-tagged

• Cat.No.: GJB1-1579H
• Product Overview: Recombinant Human GJB1 Protein (Met1-Thr130) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 44.7 kDa
  Accurate Molecular Mass: 44 kDa
• Protein length: Met1-Thr130
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: GJB1 gap junction protein, beta 1, 32kDa [ Homo sapiens (human) ]
• Official Symbol: GJB1
• Synonyms: GJB1; gap junction protein, beta 1, 32kDa; CMTX, CMTX1, gap junction protein, beta 1, 32kD (connexin 32, Charcot Marie Tooth neuropathy, X linked), gap junction protein, beta 1, 32kDa (connexin 32), gap junction protein, beta 1, 32kDa (connexin 32, Charcot Marie Tooth neuropathy, X linked); gap junction beta-1 protein; Charcot Marie Tooth neuropathy; X linked; connexin 32; CX32; connexin-32; GAP junction 28 kDa liver protein; CMTX; CMTX1
• Gene ID: 2705
• mRNA Refseq: NM_000166
• Protein Refseq: NP_000157
• MIM: 304040
• UniProt ID: P08034