| Description : |
This gene encodes a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
58.8 kDa |
| AA Sequence : |
MARGAEGGRGDAGWGLRGALAAVAL LSALNAAGTVFALCQWRGLSSALRA LEAQRGREQREDSALRSFLAELSRA PRGASAPPQDPASSARNKRSHSGEP APHIRAESHDMLMMMTYSMVPIRVM VDLCNSTKGICLTGPSGPPGPPGAG GLPGHNGLDGQPGPQGPKGEKGANG KRGKMGIPGAAGNPGERGEKGDHGE LGLQGNEGPPGQKGEKGDKGDVSND VLLAGAKGDQGPPGPPGPPGPPGPP GPPGSRRAKGPRQPSMFNGQCPGET CAIPNDDTLVGKADEKASEHHSPQA ESMITSIGNPVQVLKVTETFGTWIR ESANKSDDRIWVTEHFSGIMVKEFK DQPSLLNGSYTFIHLPYYFHGCGHV VYNNSLYYHKGGSNTLVRFEFGQET SQTLKLENALYFDRKYLFANSKTYF NLAVDEKGLWIIYASSVDGSSILVA QLDERTFSVVQHVNTTYPKSKAGNA FIARGILYVTDTKDMRVTFAFDLLG GKQINANFDLRTSQSVLAMLAYNMR DQHLYSWEDGHLMLYPVQFLSTTLN QTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
