Recombinant Human GLRX2 Protein

• Cat.No.: GLRX2-153H
• Product Overview: Recombinant Human GLRX2 Protein (D41-164) (exons 1a-IV)

Specification

• Description: The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.
• Species: Human
• Form: Lyophilized
• Stability: ≥ 1 year
• Storage: At -80 centigrade.
• Concentration: Concentration of glutaredoxin before lyophilization was 457 μM.
• Storage Buffer: Lyophilized from 50 mM tris-HCl-1 mM EDTA, pH 7.5
• Reconstitution: Reconstitute with water or buffer.

Gene Information

• Gene Name: GLRX2 glutaredoxin 2 [ Homo sapiens (human) ]
• Official Symbol: GLRX2
• Synonyms: GLRX2; glutaredoxin 2; GRX2; CGI-133; glutaredoxin 2; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); glutaredoxin (thioltransferase) 2
• Gene ID: 51022
• mRNA Refseq: NM_016066
• Protein Refseq: NP_057150
• MIM: 606820
• UniProt ID: Q9NS18