Recombinant Human GLUD1 Protein, GST-tagged

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Recombinant Human GLUD1 Protein, GST-tagged

GLUD1 Related Products

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Cat.No. : GLUD1-4991H
Product Overview : Human GLUD1 full-length ORF (BAG52930.1, 1 a.a. - 515 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 82.4 kDa
AA Sequence : MYRYLGPGTA RRRPAAGAGI GRPAPLQRGG GRPRGRPQLL QDGGGLLRSR RQHRGGQAGG GPEDPGERGA EAEPGARHPA DHQALQPCAE SLLPQHSQHR TPCKGGIRYS TDVSVDEVKA LASLMTYKCA VVDVPFGGAK AGVKINPKNY TDNELEKITR RFTMELAKKG FIGPGIDVPA PDMSTGEREM SWIADTYAST IGHYDINAHA CVTGKPISQG GIHGRISATG RGVFHGIENF INEASYMSIL GMTPGFGDKT FVVQGFGNVG LHSMRYLHRF GAKCIAVGES DGSIWNPDGI DPKELEDFKL QHGSILGFPK AKPYEGSILE ADCDILIPAA SEKQLTKSNA PRVKAKIIAE GANGPTTPEA DKIFLERNIM VIPDLYLNAG GVTVSYFEWL KNLNHVSYGR LTFKYERDSN YHLLMSVQES LERKFGKHGG TIPIVPTAEF QDRISGASEK DIVHSGLAYT VERSARQIMR TAMKYNLGLD LRTAAYVNAI EKVFKVYNEA GVTFT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GLUD1 glutamate dehydrogenase 1 [ Homo sapiens ]
Official Symbol : GLUD1
Synonyms : GLUD1; glutamate dehydrogenase 1; GLUD; glutamate dehydrogenase 1, mitochondrial; GDH; GDH 1; glutamate dehydrogenase (NAD(P)+); GDH1; MGC132003;
Gene ID : 2746
mRNA Refseq : NM_005271
Protein Refseq : NP_005262
MIM : 138130
UniProt ID : P00367

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