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Recombinant Human GLUL Protein, His-tagged

Cat.No. : GLUL-153H
Product Overview : Recombinant Human GLUL(Thr2-Asn373), transcript variant 1, fused with His tag at C-terminal was expressed in E. coli.
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  • Gene Information
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Description : The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : His
Form : Supplied as a 0.2 µM filtered solution of 20mM Tris-HCl, 200mM NaCl, 50mM Imidazole, pH 8.0
Molecular Mass : 43.0 kDa
Protein length : Thr2-Asn373
Endotoxin : < 0.1 EU per µg protein as determined by LAL test
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : GLUL glutamate-ammonia ligase [ Homo sapiens ]
Official Symbol : GLUL
Synonyms : GLUL; glutamate-ammonia ligase; GLNS, glutamate ammonia ligase (glutamine synthase); glutamine synthetase; glutamine synthase; glutamate decarboxylase; glutamate--ammonia ligase; proliferation-inducing protein 43; cell proliferation-inducing protein 59; GS; GLNS; PIG43; PIG59;
Gene ID : 2752
mRNA Refseq : NM_002065
Protein Refseq : NP_002056
MIM : 138290
UniProt ID : P15104

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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