Recombinant Human Glutathione S-transferase Omega 1

• Cat.No.: GSTO1-498H
• Product Overview: Recombinant human GSTO1 protein was expressed inE.coliand purified by using conventional chromatography techniques, 27.5 kDa (241aa).

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: GSTO1, also known as p28 or GSTTLp28, is a protein that localizes to the cytoplasm and contains both an N-terminal and a C-terminal GST domain.In mouse, the encoded protein acts as a small stress response protein, likely involved in cellular redox homeostasis. This protein has dehydroascorbate reductase activity and may function in the glutathione-ascorbate cycle as part of antioxidant metabolism.
• Sequences Of Amino Acids: MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL VLKAKGIRHE VININLKNKP EWFFKKNPFG LVPVLENSQG QLIYESAITC EYLDEAYPGK KLLPDDPYEK ACQKMILELF SKVPSLVGSF IRSQNKEDYA GLKEEFRKEF TKLEEVLTNK KTTFFGGNSI SMIDYLIWPW FERLEAMKLN ECVDHTPKLK LWMAAMKEDP TVSALLTSEK DWQGFLELYL QNSPEACDYG L.
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT and 10% glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Drug metabolism - cytochrome P450; Glutathione metabolism; Metabolism of xenobiotics by cytochrome P450; Biological oxidations; Metabolism of vitamins and cofactors

Gene Information

• Gene Name: GSTO1 glutathione S-transferase omega 1 [ Homo sapiens ]
• Synonyms: P28; GSTTLp28; DKFZp686H13163; GSTO1; glutathione S-transferase omega 1; glutathione S-transferase omega-1; GSTO-1; glutathione-S-transferase like; glutathione transferase omega 1; glutathione S-transferase omega 1-1; GSTO 1-1; glutathione-S-transferase omega 1; EC 2.5.1.18; GSTTLP28
• Gene ID: 9446
• mRNA Refseq: NM_004832
• Protein Refseq: NP_004823
• MIM: 605482
• UniProt ID: P78417
• Chromosome Location: 10q25.1
• Function: glutathione transferase activity; monodehydroascorbate reductase (NADH) activity; transferase activity