Recombinant Human GMDS Protein, GST-tagged

• Cat.No.: GMDS-5005H
• Product Overview: Human GMDS full-length ORF ( AAH00117, 1 a.a. - 372 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.66 kDa
• AA Sequence: MAHAPARCPSARGSGDGEMGKPRNV ALITGITGQDGSYLAEFLLEKGYEV HGIVRRSSSFNTGRIEHLYKNPQAH IEGNMKLHYGDLTDSTCLVKIINEV KPTEIYNLGAQSHVKISFDLAEYTA DVDGVGTLRLLDAVKTCGLINSVKF YQASTSELYGKVQEIPQKETTPFYP RSPYGAAKLYAYWIVVNFREAYNLF AVNGILFNHESPRRGANFVTRKISR SVAKIYLGQLECFSLGNLDAKRDWG HAKDYVEAMWLMLQNDEPEDFVIAT GEVHSVREFVEKSFLHIGKTIVWEG KNENEVGRCKETGKVHVTVDLKYYR PTEVDFLQGDCTKAKQKLNWKPRVA FDELVREMVHADVELMRTNPNA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GMDS GDP-mannose 4,6-dehydratase [ Homo sapiens ]
• Official Symbol: GMDS
• Synonyms: GMDS; GDP-mannose 4,6-dehydratase; GDP-mannose 4,6 dehydratase; GMD; SDR3E1; short chain dehydrogenase/reductase family 3E; member 1; GDP-D-mannose dehydratase; short chain dehydrogenase/reductase family 3E, member 1
• Gene ID: 2762
• mRNA Refseq: NM_001253846
• Protein Refseq: NP_001240775
• MIM: 602884
• UniProt ID: O60547