| Description : |
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
76.7 kDa |
| AA Sequence : |
MALCNGDSKLENAGGDLKDGHHHYE GAVVILDAGAQYGKVIDRRVRELFV QSEIFPLETPAFAIKEQGFRAIIIS GGPNSVYAEDAPWFDPAIFTIGKPV LGICYGMQMMNKVFGGTVHKKSVRE DGVFNISVDNTCSLFRGLQKEEVVL LTHGDSVDKVADGFKVVARSGNIVA GIANESKKLYGAQFHPEVGLTENGK VILKNFLYDIAGCSGTFTVQNRELE CIREIKERVGTSKVLVLLSGGVDST VCTALLNRALNQEQVIAVHIDNGFM RKRESQSVEEALKKLGIQVKVINAA HSFYNGTTTLPISDEDRTPRKRISK TLNMTTSPEEKRKIIGDTFVKIANE VIGEMNLKPEEVFLAQGTLRPDLIE SASLVASGKAELIKTHHNDTELIRK LREEGKVIEPLKDFHKDEVRILGRE LGLPEELVSRHPFPGPGLAIRVICA EEPYICKDFPETNNILKIVADFSAS VKKPHTLLQRVKACTTEEDQEKLMQ ITSLHSLNAFLLPIKTVGVQGDCRS YSYVCGISSKDEPDWESLIFLARLI PRMCHNVNRVVYIFGPPVKEPPTDV TPTFLTTGVLSTLRQADFEAHNILR ESGYAGKISQMPVILTPLHFDRDPL QKQPSCQRSVVIRTFITSDFMTGIP ATPGNEIPVEVVLKMVTEIKKIPGI SRIMYDLTSKPPGTTEWETRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
