Recombinant Human GMPS, GST-tagged

• Cat.No.: GMPS-13341H
• Product Overview: Recombinant Human GMPS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 345-693a.a.
• Description: This gene encodes a transmembrane connexin protein that is a component of gap junctions. Mutations in this gene have been associated with erythrokeratodermia variabilis, progressive symmetric erythrokeratoderma and hearing impairment.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GMPS guanine monphosphate synthetase [ Homo sapiens ]
• Official Symbol: GMPS
• Synonyms: GMPS; guanine monphosphate synthetase; GMP synthase [glutamine-hydrolyzing]; GMP synthase; GMP synthetase; MLL/GMPS fusion protein; glutamine amidotransferase; guanosine 5-monophosphate synthase
• Gene ID: 8833
• mRNA Refseq: NM_003875
• Protein Refseq: NP_003866
• MIM: 600358
• UniProt ID: P49915
• Chromosome Location: 3q25.31
• Pathway: Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, organism-specific biosystem
• Function: ATP binding; GMP synthase (glutamine-hydrolyzing) activity; GMP synthase activity; ligase activity; nucleotide binding