Active Recombinant Human GNMT Protein, His-tagged, Bioactivity Validated
Cat.No. : | GNMT-232H |
Product Overview : | Recombinant Human GNMT(1-295aa) fused with His tag at N-terminal was expressed in E. coli. Bioactivity Validated. |
- Specification
- Gene Information
- Related Products
Description : | Glycine N-methyltransferase, also known as GNMT, catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. This protein affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine and participates in the detoxification pathway in liver cells. Also it is reported that GNMT expression is diminished in human hepatocellular carcinoma (HCC). |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol |
Bio-activity : | Specific activity is > 100 nmol/min/mg, and is defined as the amount of enzyme that transfer 1.0 nmole of methyl group per minute at 37C. |
Molecular Mass : | 34.9 kDa (315aa), confirmed by MALDI-TOF |
Protein length : | 1-295aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MVDSVYRTRS LGVAAEGLPD QYADGEAARV WQLYIGDTRS RTAEYKAWLL GLLRQHGCQR VLDVACGTGV DSIMLVEEGF SVTSVDASDK MLKYALKERW NRRHEPAFDK WVIEEANWMT LDKDVPQSAE GGFDAVICLG NSFAHLPDCK GDQSEHRLAL KNIASMVRAG GLLVIDHRNY DHILSTGCAP PGKNIYYKSD LTKDVTTSVL IVNNKAHMVT LDYTVQVPGA GQDGSPGLSK FRLSYYPHCL ASFTELLQAA FGGKCQHSVL GDFKPYKPGQ TYIPCYFIHV LKRTD |
Purity : | > 95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Absorbance at 280nm) |
Gene Name : | GNMT glycine N-methyltransferase [ Homo sapiens ] |
Official Symbol : | GNMT |
Synonyms : | GNMT; glycine N-methyltransferase; |
Gene ID : | 27232 |
mRNA Refseq : | NM_018960 |
Protein Refseq : | NP_061833 |
MIM : | 606628 |
UniProt ID : | Q14749 |
Products Types
◆ Recombinant Protein | ||
GNMT-1730R | Recombinant Rhesus Macaque GNMT Protein, His (Fc)-Avi-tagged | +Inquiry |
Gnmt-1041M | Recombinant Mouse Gnmt Protein, MYC/DDK-tagged | +Inquiry |
GNMT-2267R | Recombinant Rat GNMT Protein, His (Fc)-Avi-tagged | +Inquiry |
GNMT-5086H | Recombinant Human GNMT Protein, GST-tagged | +Inquiry |
GNMT-577H | Recombinant Human GNMT Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GNMT-5844HCL | Recombinant Human GNMT 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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