Recombinant Human Golgi associated PDZ and coiled-coil motif containing, His-tagged
Cat.No. : | GOPC-1941H |
Product Overview : | Recombinant human GOPC protein fused to his-tag was expressed inE.coliand purified by using conventional chromatography techniques. 21.5 kDa (198aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | GOPC-1941H |
Description : | GOPC, also known as PIST, is a PDZ domain-containing Golgi protein. This protein functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation. Additionally, GOPC is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy. Chromosomal aberrations in the gene encoding GOPC are found in glioblastoma multiform (GBM), a common and aggressive form of brain tumor, suggesting a role for mutated PIST in carcinogenesis. |
Source : | E.coli. |
Purity : | > 90% by SDS – PAGE. |
Physical Appearance : | Liquid. |
Formulation : | In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MIRKVLLLKE DHEGLGISIT GGK EHGVPIL ISEIHPGQPA DRCGGLHVGD AILAVNGVNL RDTKHKEAVT ILSQ QRGEIE FEVVYVAPEV DSDDENVEYE DESGHRYRLY LDEL EGGGNP GASCKDTSGE IKVLQGFNKK AVTDTHENGD LGTASETPLD DGASKLDDLH TLYHKKSY. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | GOPC golgi-associated PDZ and coiled-coil motif containing [ Homo sapiens ] |
Synonyms : | GOPC; golgi associated PDZ and coiled-coil motif containing; CAL; FIG; PIST; GOPC1; AI844555; 2210402P09Rik; PDZ domain-containing protein PIST; PDZ protein interacting specifically with TC10; golgi-associated PDZ and coiled-coil motif-containing protein; dJ94G16.2; Fused in glioblastoma; CFTR-associated ligand; Golgi associated PDZ and coiled-coil motif containing protein; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10. |
Gene ID : | 57120 |
mRNA Refseq : | NM_001017408 |
Protein Refseq : | NP_001017408 |
MIM : | 606845 |
UniProt ID : | Q9HD26 |
Chromosome Location : | 6q21 |
Function : | cystic fibrosis transmembrane conductance regulator binding; protein binding; small GTPase regulator activity |
Products Types
◆ Recombinant Protein | ||
GOPC-3800M | Recombinant Mouse GOPC Protein, His (Fc)-Avi-tagged | +Inquiry |
GOPC-5118H | Recombinant Human GOPC Protein, His-tagged | +Inquiry |
Gopc-3272M | Recombinant Mouse Gopc Protein, Myc/DDK-tagged | +Inquiry |
GOPC-119H | Recombinant Human GOPC protein, His-tagged | +Inquiry |
GOPC-27637TH | Recombinant Human GOPC, His-tagged | +Inquiry |
◆ Lysates | ||
GOPC-5831HCL | Recombinant Human GOPC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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