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Recombinant Human GPER1 protein, GST-tagged

Cat.No. : GPER1-12H
Product Overview : Recombinant Human GPER1(1 a.a. - 375 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
  • Specification
  • Gene Information
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Description : This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 68.6 kDa
AA Sequence : MDVTSQARGVGLEMYPGTAQPAAPN TTSPELNLSHPLLGTALANGTGELS EHQQYVIGLFLSCLYTIFLFPIGFV GNILILVVNISFREKMTIPDLYFIN LAVADLILVADSLIEVFNLHERYYD IAVLCTFMSLFLQVNMYSSVFFLTW MSFDRYIALARAMRCSLFRTKHHAR LSCGLIWMASVSATLVPFTAVHLQH TDEACFCFADVREVQWLEVTLGFIV PFAIIGLCYSLIVRVLVRAHRHRGL RPRRQKALRMILAVVLVFFVCWLPE NVFISVHLLQRTQPGAAPCKQSFRH AHPLTGHIVNLAAFSNSCLNPLIYS FLGETFRDKLRLYIEQKTNLPALNR FCHAALKAVIPDSTEQSDVRFSSAV
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : GPER1 G protein-coupled estrogen receptor 1 [ Homo sapiens ]
Official Symbol : GPER1
Synonyms : mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br; G protein-coupled receptor 30; IL8-related receptor DRY12; chemoattractant receptor-like 2; chemokine receptor-like 2; constitutively expressed peptide-like receptor; flow-induced endothelial G-protein coupled receptor 1; heptahelix receptor; leucine rich protein in GPR30 3'UTR; lymphocyte-derived G-protein coupled receptor; membrane estrogen receptor
Gene ID : 2852
mRNA Refseq : NM_001505
Protein Refseq : NP_001496
MIM : 601805
UniProt ID : Q99527
Chromosome Location : 7p22.3
Pathway : Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Estrogen signaling pathway, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem
Function : G-protein coupled receptor activity; mineralocorticoid receptor activity; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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