Recombinant Human GPER1 protein, GST-tagged
Cat.No. : | GPER1-12H |
Product Overview : | Recombinant Human GPER1(1 a.a. - 375 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
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Description : | This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 68.6 kDa |
AA Sequence : | MDVTSQARGVGLEMYPGTAQPAAPN TTSPELNLSHPLLGTALANGTGELS EHQQYVIGLFLSCLYTIFLFPIGFV GNILILVVNISFREKMTIPDLYFIN LAVADLILVADSLIEVFNLHERYYD IAVLCTFMSLFLQVNMYSSVFFLTW MSFDRYIALARAMRCSLFRTKHHAR LSCGLIWMASVSATLVPFTAVHLQH TDEACFCFADVREVQWLEVTLGFIV PFAIIGLCYSLIVRVLVRAHRHRGL RPRRQKALRMILAVVLVFFVCWLPE NVFISVHLLQRTQPGAAPCKQSFRH AHPLTGHIVNLAAFSNSCLNPLIYS FLGETFRDKLRLYIEQKTNLPALNR FCHAALKAVIPDSTEQSDVRFSSAV |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | GPER1 G protein-coupled estrogen receptor 1 [ Homo sapiens ] |
Official Symbol : | GPER1 |
Synonyms : | mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br; G protein-coupled receptor 30; IL8-related receptor DRY12; chemoattractant receptor-like 2; chemokine receptor-like 2; constitutively expressed peptide-like receptor; flow-induced endothelial G-protein coupled receptor 1; heptahelix receptor; leucine rich protein in GPR30 3'UTR; lymphocyte-derived G-protein coupled receptor; membrane estrogen receptor |
Gene ID : | 2852 |
mRNA Refseq : | NM_001505 |
Protein Refseq : | NP_001496 |
MIM : | 601805 |
UniProt ID : | Q99527 |
Chromosome Location : | 7p22.3 |
Pathway : | Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Estrogen signaling pathway, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem |
Function : | G-protein coupled receptor activity; mineralocorticoid receptor activity; protein binding |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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