| Description : |
This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
83.4 kDa |
| AA Sequence : |
MATEGMILTNHDHQIRVGVLTVSDS CFRNLAEDRSGINLKDLVQDPSLLG GTISAYKIVPDEIEEIKETLIDWCD EKELNLILTTGGTGFAPRDVTPEAT KEVIEREAPGMALAMLMGSLNVTPL GMLSRPVCGIRGKTLIINLPGSKKG SQECFQFILPALPHAIDLLRDAIVK VKEVHDELEDLPSPPPPLSPPPTTS PHKQTEDKGVQCEEEEEEKKDSGVA STEDSSSSHITAAAIAAKKHPFYTS PAVVMAHGEQPIPGLINYSHHSTDE RIPDSIISRGVQVLPRDTASLSTTP SESPRAQATSRLSTASCPTPKVQSR CSSKENILRASHSAVDITKVARRHR MSPFPLTSMDKAFITVLEMTPVLGT EIINYRDGMGRVLAQDVYAKDNLPP FPASVKDGYAVRAADGPGDRFIIGE SQAGEQPTQTVMPGQVMRVTTGAPI PCGADAVVQVEDTELIRESDDGTEE LEVRILVQARPGQDIRPIGHDIKRG ECVLAKGTHMGPSEIGLLATVGVTE VEVNKFPVVAVMSTGNELLNPEDDL LPGKIRDSNRSTLLATIQEHGYPTI NLGIVGDNPDDLLNALNEGISRADV IITSGGVSMGEKDYLKQVLDIDLHA QIHFGRVFMKPGLPTTFATLDIDGV RKIIFALPGNPVSAVVTCNLFVVPA LRKMQGILDPRPTIIKARLSCDVKL DPRPEYHRCILTWHHQEPLPWAQST GNQMSSRLMSMRSANGLLMLPPKTE QYVELHKGEVVDVMVIGRLTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
