Recombinant Human GPM6A, GST-tagged
Cat.No. : | GPM6A-13428H |
Product Overview : | Recombinant Human GPM6A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Availability | July 06, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | GST |
Protein Length : | 1-278a.a. |
Description : | The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name | GPM6A glycoprotein M6A [ Homo sapiens ] |
Official Symbol | GPM6A |
Synonyms | GPM6A; glycoprotein M6A; GPM6; neuronal membrane glycoprotein M6-a; M6A; |
Gene ID | 2823 |
mRNA Refseq | NM_005277 |
Protein Refseq | NP_005268 |
MIM | 601275 |
UniProt ID | P51674 |
Chromosome Location | 4q34 |
Function | calcium channel activity; |
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Not For Human Consumption!
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