Recombinant Human GPT2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human GPT2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : GPT2-4295H
Product Overview : GPT2 MS Standard C13 and N15-labeled recombinant protein (NP_597700) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 57.9 kDa
AA Sequence : MQRAAALVRR GCGPRTPSSW GRSQSSAAAE ASAVLKVRPE RSRRERILTL ESMNPQVKAV EYAVRGPIVL KAGEIELELQ RGIKKPFTEV IRANIGDAQA MGQQPITFLR QVMALCTYPN LLDSPSFPED AKKRARRILQ ACGGNSLGSY SASQGVNCIR EDVAAYITRR DGGVPADPDN IYLTTGASDG ISTILKILVS GGGKSRTGVM IPIPQYPLYS AVISELDAIQ VNYYLDEENC WALNVNELRR AVQEAKDHCD PKVLCIINPG NPTGQVQSRK CIEDVIHFAW EEKLFLLADE VYQDNVYSPD CRFHSFKKVL YEMGPEYSSN VELASFHSTS KGYMGECGYR GGYMEVINLH PEIKGQLVKL LSVRLCPPVS GQAAMDIVVN PPVAGEESFE QFSREKESVL GNLAKKAKLT EDLFNQVPGI HCNPLQGAMY AFPRIFIPAK AVEAAQAHQM APDMFYCMKL LEETGICVVP GSGFGQREGT YHFRMTILPP VEKLKTVLQK VKDFHINFLE KYASGPTRTR PLEQKLISEE DLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GPT2 glutamic--pyruvic transaminase 2 [ Homo sapiens (human) ]
Official Symbol : GPT2
Synonyms : GPT2; glutamic pyruvate transaminase (alanine aminotransferase) 2; alanine aminotransferase 2; ALT2; GPT 2; glutamic--alanine transaminase 2; glutamic--pyruvic transaminase 2; glutamic-pyruvate transaminase 2; glutamate pyruvate transaminase 2;
Gene ID : 84706
mRNA Refseq : NM_133443
Protein Refseq : NP_597700
MIM : 138210
UniProt ID : Q8TD30

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