Recombinant Human GPX7, GST-tagged

• Cat.No.: GPX7-13511H
• Product Overview: Recombinant Human GPX7 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 58-187a.a.
• Description: This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GPX7 glutathione peroxidase 7 [ Homo sapiens ]
• Official Symbol: GPX7
• Synonyms: GPX7; glutathione peroxidase 7; FLJ14777; GPX6; NPGPx; glutathione peroxidase 6; non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase; CL683; GPx-7; GSHPx-7
• Gene ID: 2882
• mRNA Refseq: NM_015696
• Protein Refseq: NP_056511
• UniProt ID: Q96SL4
• Chromosome Location: 1p32
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; glutathione redox reactions I, organism-specific biosystem
• Function: glutathione peroxidase activity; oxidoreductase activity