Recombinant Human GRB2 Protein, DYKDDDDK-tagged
Cat.No. : | GRB2-151H |
Product Overview : | Recombinant Human growth factor receptor bound protein 2(GRB2), transcript variant 1(NM_002086), with a DYKDDDDK tag, was expressed in human cells. |
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Species : | Human |
Source : | Human Cells |
Tag : | Flag |
Description : | Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death. |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.339, without any preservatives. |
Molecular Mass : | 25 kDa |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name | GRB2 growth factor receptor-bound protein 2 [ Homo sapiens ] |
Official Symbol | GRB2 |
Synonyms | GRB2; growth factor receptor-bound protein 2; NCKAP2; HT027; protein Ash; SH2/SH3 adapter GRB2; abundant SRC homology; growth factor receptor-bound protein 3; epidermal growth factor receptor-binding protein GRB2; ASH; Grb3-3; MST084; MSTP084; EGFRBP-GRB2; |
Gene ID | 2885 |
mRNA Refseq | NM_002086 |
Protein Refseq | NP_002077 |
MIM | 108355 |
UniProt ID | P62993 |
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Not For Human Consumption!
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