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Recombinant Human GRB2 Protein, DYKDDDDK-tagged

Cat.No. : GRB2-151H
Product Overview : Recombinant Human growth factor receptor bound protein 2(GRB2), transcript variant 1(NM_002086), with a DYKDDDDK tag, was expressed in human cells.
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  • Gene Information
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Description : Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
Source : Human Cells
Species : Human
Tag : DYKDDDDK
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.339, without any preservatives.
Molecular Mass : 25 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : GRB2 growth factor receptor-bound protein 2 [ Homo sapiens ]
Official Symbol : GRB2
Synonyms : GRB2; growth factor receptor-bound protein 2; NCKAP2; HT027; protein Ash; SH2/SH3 adapter GRB2; abundant SRC homology; growth factor receptor-bound protein 3; epidermal growth factor receptor-binding protein GRB2; ASH; Grb3-3; MST084; MSTP084; EGFRBP-GRB2;
Gene ID : 2885
mRNA Refseq : NM_002086
Protein Refseq : NP_002077
MIM : 108355
UniProt ID : P62993

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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