Recombinant Human GRB2 Protein, GST-tagged

Cat.No. : GRB2-5038H
Product Overview : Human GRB2 full-length ORF ( AAH00631, 1 a.a. - 217 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 49.61 kDa
AA Sequence : MEAIAKYDFKATADDELSFKRGDIL KVLNEECDQNWYKAELNGKDGFIPK NYIEMKPHPWFFGKIPRAKAEEMLS KQRHDGAFLIRESESAPGDFSLSVK FGNDVQHFKVLRDGAGKYFLWVVKF NSLNELVDYHRSTSVSRNQQIFLRD IEQVPQQPTYVQALFDFDPQEDGEL GFRRGDFIHVMDNSDPNWWKGACHG QTGMFPRNYVTPVNRNV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
SDS-PAGE: 12.5% SDS-PAGE Stained with Coomassie Blue.
Gene Name : GRB2 growth factor receptor-bound protein 2 [ Homo sapiens ]
Official Symbol : GRB2
Synonyms : GRB2; growth factor receptor-bound protein 2; NCKAP2; HT027; protein Ash; SH2/SH3 adapter GRB2; abundant SRC homology; growth factor receptor-bound protein 3; epidermal growth factor receptor-binding protein GRB2; ASH; Grb3-3; MST084; MSTP084; EGFRBP-GRB2;
Gene ID : 2885
mRNA Refseq : NM_002086
Protein Refseq : NP_002077
MIM : 108355
UniProt ID : P62993

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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