Recombinant Human GRB2 Protein, His-GST-tagged

Cat.No. : GRB2-001H
Product Overview : Recombinant Human GRB2 Protein (1-217 aa (full-length)) with 6xHis-GST tags was expressed in E. coli.
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Description : The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His-GST
Molecular Mass : 54.1 kDa
Protein length : 1-217
Purity : >95% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB).
Applications : ELISA, Western Blot, Antibody Production, Protein array
Quality Control Test : 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-GST monoclonal and peptide fingerprinting by MALDI-TOF mass spectrometry.
Storage : Store working aliquots at 4 centigrade for up to one week. For extended storage, conserve at −80 centigrade.
Expiry : 12 months from the date of purchase, if it is properly stored.
Storage Buffer : Phosphate-Buffered Saline (PBS), pH 7.4. No preservatives added.
Shipping : Dry Ice
SDS-PAGE:
Gene Name : GRB2 growth factor receptor bound protein 2 [ Homo sapiens (human) ]
Official Symbol : GRB2
Synonyms : GRB2; growth factor receptor bound protein 2; ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2; growth factor receptor-bound protein 2; HT027; SH2/SH3 adapter; GRB2; abundant SRC homology; epidermal growth factor receptor-binding protein GRB2; epididymis secretory sperm binding protein; growth factor receptor-bound protein 3; protein Ash
Gene ID : 2885
mRNA Refseq : NM_002086
Protein Refseq : NP_002077
MIM : 108355
UniProt ID : P62993

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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