Recombinant Human GRHL2 Protein, GST-tagged

• Cat.No.: GRHL2-5326H
• Product Overview: Human GRHL2 full-length ORF ( NP_079191.1, 1 a.a. - 625 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28)
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 97.5 kDa
• AA Sequence: MSQESDNNKRLVALVPMPSDPPFNT RRAYTSEDEAWKSYLENPLTAATKA MMSINGDEDSAAALGLLYDYYKVPR DKRLLSVSKASDSQEDQEKRNCLGT SEAQSNLSGGENRVQVLKTVPVNLS LNQDHLENSKREQYSISFPESSAII PVSGITVVKAEDFTPVFMAPPVHYP RGDGEEQRVVIFEQTQYDVPSLATH SAYLKDDQRSTPDSTYSESFKDAAT EKFRSASVGAEEYMYDQTSSGTFQY TLEATKSLRQKQGEGPMTYLNKGQF YAITLSETGDNKCFRHPISKVRSVV MVVFSEDKNRDEQLKYWKYWHSRQH TAKQRVLDIADYKESFNTIGNIEEI AYNAVSFTWDVNEEAKIFITVNCLS TDFSSQKGVKGLPLMIQIDTYSYNN RSNKPIHRAYCQIKVFCDKGAERKI RDEERKQNRKKGKGQASQTQCNSSS DGKLAAIPLQKKSDITYFKTMPDLH SQPVLFIPDVHFANLQRTGQVYYNT DDEREGGSVLVKRMFRPMEEEFGPV PSKQMKEEGTKRVLLYVRKETDDVF DALMLKSPTVKGLMEAISEKYGLPV EKIAKLYKKSKKGILVNMDDNIIEH YSNEDTFILNMESMVEGFKVTLMEI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GRHL2 grainyhead-like 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: GRHL2
• Synonyms: GRHL2; grainyhead-like 2 (Drosophila); deafness, autosomal dominant 28, DFNA28, TFCP2L3, transcription factor CP2 like 3; grainyhead-like protein 2 homolog; BOM; FLJ13782; brother of mammalian grainyhead; transcription factor CP2-like 3; DFNA28; TFCP2L3; FLJ11172; MGC149294; MGC149295
• Gene ID: 79977
• mRNA Refseq: NM_024915
• Protein Refseq: NP_079191
• MIM: 608576
• UniProt ID: Q6ISB3